Thanks, Mike! My sis is on this. She’s lost 40+ lbs within 9 mos! She thinks this may become a wonder drug for all to take, even if not overweight or diabetic, because she said it supposedly does so many wonderful things. Dr. Mike, what do you think?

 I haven’t seriously considered taking them as I’m at pretty close to normal weight (~24.5 BMI) and not even pre-diabetic with generally good health (per bloodwork re: kidneys, heart, digestive system (reflux/prostate controlled well by meds), lungs, heart) other than some arthritis mainly in my hands. I take a low dose statin.

 Brainwise, I’m having more trouble thinking of words/names than I used to, but I think that’s normal as we age. I’ll be talking to someone and will ask, “what’s the word or what’s his name? a lot. These are words/names well known to me. I’m not worrying about it. 

I’ve never been good at thinking about more than one thing at a time and multi-tasking, but I think I’m usually pretty good at the one thing I’m thinking about.

Thanks for asking for my opinion, Larry!

My family has been lucky to live in this age because we all have fast metabolisms, especially me. 

If I was living hundreds of years ago in a place where people died from starvation because of one of the many famines, I would be one of the first to go.

In this age, it's a blessing that allows me to eat lot of food. I eat extremely healthy food with almost no exceptions and couldn't get fat if I tried on that diet. In fact, when I'm especially active, my body weight gets lower than I want it to be.

Congrats to your sister for her huge weight loss!!!  I empathize with people that struggle to keep their weight down and give thanks that it isn't me. I've heard many stories like this. 

This is a miracle drug for people like her.  Being obese is so horrible on our bodies for most people. 

When we see people in their 90's, how many of them are obese???

Not many by my recollection (which is  not scientific) because obesity is strongly correlated with chronic, life shortening diseases.  However, in this age of treating those diseases, obese people are living longer.

I just remembered that I had occasional severe hypoglycemia episodes thru my first 40 years. Part of this was from my pancreas being over active but also I was a body builder with a ton of muscle for my frame and muscle requires a ton of calories to sustain(higher metabolism).

My wife had gestational diabetes with our last 2 kids. When she did her first 5 hour glucose tolerance test, I asked the doctor to order one for me.

When the results came back after 1 and 2 hours, he said it was the lowest blood sugar that anybody had ever seen(in the 50's) and they were surprised I didn't pass out. 

Granted, almost everybody else had diabetes or suspected diabetes/high blood sugar but it showed that when I ate something with sugar, my pancreas gushed out TOO MUCH insulin. Fortunately, I've always eaten a low sugar diet and my pancreas isn't doing that any more. 

That glucose tolerance test has to be one of the WORST ones out there on the body to test a disease. 

The disease causes high blood sugar and the treatment is to severely restrict sugar in the person's diet.  The test?

Chug down a massive amount of concentrated sugar, the worst thing possible to test HOW BAD it is for aggravating the disease.

It would be like taking a person with a broken leg and making them run on a treadmill for 5 minutes to observe how bad it is